{"product_id":"5-amino-1mq-10mg","title":"5-Amino-1MQ 10mg","description":"\u003cp\u003e\u003cstrong\u003eBuy high-purity 5-Amino-1MQ in Australia (10mg). Third-party lab tested at \u0026gt;99% purity. Australian-domestic shipping, AUD pricing, supplied for laboratory research use only.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eAbout 5-Amino-1MQ\u003c\/h2\u003e\n\u003cp\u003e5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule research compound and a selective inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT consumes S-adenosylmethionine (SAM) and methylates nicotinamide, depleting cellular methyl pools and downstream NAD+ precursors; pharmacological inhibition of NNMT has therefore become a major focus in laboratory research on adipose-tissue energy balance, methyl-donor recycling, and metabolic resilience.\u003c\/p\u003e\n\u003cp\u003eOptic Labs supplies 5-Amino-1MQ as a lyophilised research-grade powder for laboratories investigating NNMT-mediated metabolic pathways, adipocyte biology, and ageing-related cellular remodelling. Each vial is third-party HPLC verified at \u0026gt;99% purity. 5-Amino-1MQ is supplied for laboratory research use only and is not intended for human consumption, cosmetic application, or any therapeutic purpose.\u003c\/p\u003e\n\n\u003ch2\u003eProduct specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e 5-Amino-1-methylquinolinium iodide (5-Amino-1MQ)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 75413-77-3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C\u003csub\u003e10\u003c\/sub\u003eH\u003csub\u003e11\u003c\/sub\u003eIN\u003csub\u003e2\u003c\/sub\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e ~286.1 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e Small-molecule NNMT inhibitor (not a peptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% by HPLC\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvailable sizes:\u003c\/strong\u003e 10mg vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e 2–8°C, protect from light. Reconstituted: 2–8°C, used within 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Manufactured to research-grade specifications, third-party HPLC verified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShipping:\u003c\/strong\u003e Australia-wide domestic dispatch from Sydney, NSW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch background\u003c\/h2\u003e\n\u003cp\u003e5-Amino-1MQ emerged from medicinal-chemistry programmes screening for selective NNMT inhibitors. NNMT had previously been identified as upregulated in obese adipose tissue, several solid tumours, and ageing tissue more broadly, where its activity correlates with depleted SAM and elevated 1-methylnicotinamide (MNA). 5-Amino-1MQ binds the NNMT active site with high selectivity and is widely used in published research as a chemical probe for NNMT function.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNNMT enzyme inhibition\u003c\/strong\u003e — biochemical studies have characterised 5-Amino-1MQ as a potent, selective NNMT inhibitor in cell-free and cell-culture assays.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdipocyte energy expenditure\u003c\/strong\u003e — published animal models have explored NNMT inhibition with 5-Amino-1MQ in diet-induced-obesity rodents, examining adipose-tissue mass, energy expenditure, and metabolic markers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSAM and methyl-donor pools\u003c\/strong\u003e — laboratory work has tracked changes in cellular SAM, SAH and 1-methylnicotinamide levels following NNMT inhibition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+ salvage interactions\u003c\/strong\u003e — research has examined the relationship between NNMT activity, nicotinamide availability and downstream NAD+ salvage flux.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkeletal muscle ageing models\u003c\/strong\u003e — preclinical investigation has explored NNMT inhibition in models of age-related muscle dysfunction and stem-cell quiescence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCancer-cell metabolism studies\u003c\/strong\u003e — NNMT is overexpressed in several cancer cell lines, and 5-Amino-1MQ has been used in vitro to characterise its role in tumour metabolism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatic lipid handling\u003c\/strong\u003e — animal-model studies have examined hepatic steatosis and lipid metabolism following NNMT inhibition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor broader context on metabolic and longevity peptide research, see our \u003ca href=\"\/blogs\/news\/nad-plus-australia-longevity-research-guide\"\u003eNAD+ longevity research guide\u003c\/a\u003e and our \u003ca href=\"\/blogs\/news\/what-are-peptides-australia-explainer\"\u003ewhat are peptides explainer\u003c\/a\u003e. Researchers working with reconstitution should also reference our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003epeptide reconstitution guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eReconstitution and handling\u003c\/h2\u003e\n\u003cp\u003e5-Amino-1MQ is supplied as a lyophilised powder and is reconstituted prior to use with sterile \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e. A common laboratory approach is to add 2 mL of bac water to a 10mg vial, yielding a 5 mg\/mL working concentration; at this concentration, 0.1 mL drawn into an insulin syringe corresponds to 500 µg of compound. As 5-Amino-1MQ is a small molecule rather than a long-chain peptide, it is generally well behaved in solution. Reconstituted material should be stored at 2–8°C, protected from light, and used within 30 days. For step-by-step dilution mathematics, see our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e and our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage research guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eCommonly stacked research peptides\u003c\/h2\u003e\n\u003cp\u003eIn published metabolic and longevity research, 5-Amino-1MQ is often referenced alongside other compounds investigated for energy-expenditure, NAD+ and methyl-pool research:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/nad-1000mg\"\u003eNAD+\u003c\/a\u003e — directly relevant to the methyl\/nicotinamide axis modulated by NNMT inhibition.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/reta-10mg-15mg-20mg-30mg\"\u003eRetatrutide\u003c\/a\u003e — GLP-1\/GIP\/glucagon triple agonist studied in adiposity and metabolic-rate research.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/aod-9604-5mg\"\u003eAOD-9604\u003c\/a\u003e — hGH (177–191) fragment investigated for adipose lipolysis research.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/mots-c-10mg-40mg\"\u003eMOTS-c\u003c\/a\u003e — mitochondrial-derived peptide investigated in metabolic and ageing models.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/glutathione-1500mg\"\u003eGlutathione\u003c\/a\u003e — tripeptide antioxidant cross-referenced with 5-Amino-1MQ in redox and methyl-pool research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor broader context on multi-compound research designs, see our \u003ca href=\"\/blogs\/news\/peptide-research-stacks-australia-combinations\"\u003epeptide research stacks overview\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\n\u003ch3\u003eIs 5-Amino-1MQ legal in Australia?\u003c\/h3\u003e\n\u003cp\u003e5-Amino-1MQ is supplied by Optic Labs strictly for laboratory research, development and analytical use. It is not approved by the Therapeutic Goods Administration for human therapeutic use and is not a registered medicine. For a detailed overview of Australian research-compound regulation, see our \u003ca href=\"\/blogs\/news\/are-peptides-legal-australia-tga-compliance-2025\"\u003eguide to peptide legality and TGA compliance in Australia\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhat is 5-Amino-1MQ?\u003c\/h3\u003e\n\u003cp\u003e5-Amino-1MQ is a small-molecule research compound that selectively inhibits nicotinamide N-methyltransferase (NNMT). It is not a peptide; it is a methylated quinolinium derivative used as a chemical probe in metabolic and ageing research. See our \u003ca href=\"\/blogs\/news\/what-are-peptides-australia-explainer\"\u003ewhat are peptides explainer\u003c\/a\u003e for broader context on the wider research-compound landscape.\u003c\/p\u003e\n\n\u003ch3\u003eWhat does 5-Amino-1MQ research focus on?\u003c\/h3\u003e\n\u003cp\u003ePublished research has examined 5-Amino-1MQ in cell-culture and animal models of obesity, adipose-tissue energy expenditure, NAD+\/SAM methyl-pool dynamics, hepatic lipid metabolism and ageing-related cellular function. It is studied as an NNMT inhibitor rather than a metabolic or weight-loss treatment.\u003c\/p\u003e\n\n\u003ch3\u003eHow is 5-Amino-1MQ supplied?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs supplies 5-Amino-1MQ as a lyophilised powder in glass research vials, available in 10mg. Each vial is sealed and shipped with a tamper-evident seal. Certificates of analysis showing HPLC purity testing are available on request.\u003c\/p\u003e\n\n\u003ch3\u003eHow much bacteriostatic water do I mix with a 5-Amino-1MQ 10mg vial?\u003c\/h3\u003e\n\u003cp\u003eA common laboratory dilution is 2 mL of \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e per 10mg vial, giving a 5 mg\/mL solution. The exact volume depends on your research protocol — see our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e for dilution mathematics.\u003c\/p\u003e\n\n\u003ch3\u003eHow should reconstituted 5-Amino-1MQ be stored?\u003c\/h3\u003e\n\u003cp\u003eReconstituted 5-Amino-1MQ should be kept at 2–8°C, protected from light, and used within 30 days. Long-term storage of unreconstituted lyophilised powder should be at −20°C or colder. See our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage complete research guide\u003c\/a\u003e for handling detail.\u003c\/p\u003e\n\n\u003ch3\u003eWhere does Optic Labs ship to?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs ships Australia-wide from Sydney, NSW. Standard dispatch is next business day on orders received before the daily cut-off. International shipping is not currently offered.\u003c\/p\u003e\n\n\u003ch2\u003eLegal disclaimer\u003c\/h2\u003e\n\u003cp\u003eAll products on this site are supplied for \u003cstrong\u003elaboratory research, development or analytical use only\u003c\/strong\u003e. They are not for human consumption, clinical use, or any diagnostic, cosmetic or veterinary application. These products and statements have not been evaluated by the \u003cstrong\u003eTherapeutic Goods Administration (TGA)\u003c\/strong\u003e or the \u003cstrong\u003eAPVMA\u003c\/strong\u003e and are not intended to diagnose, treat, cure or prevent any disease. Optic Labs is not a \u003cstrong\u003ecompounding pharmacy\u003c\/strong\u003e or manufacturing facility as defined under the \u003cem\u003eTherapeutic Goods Act 1989\u003c\/em\u003e, and is not a registered provider of scheduled medicines or therapeutic goods.\u003c\/p\u003e","brand":"Optic Labs","offers":[{"title":"Default Title","offer_id":53360885137592,"sku":null,"price":71.99,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0952\/4196\/1656\/files\/5-amino-moq_e958a6b6-e671-4502-a582-1ec7d515da55.png?v=1776427234","url":"https:\/\/opticlabsau.com\/products\/5-amino-1mq-10mg","provider":"Optic Labs","version":"1.0","type":"link"}