{"product_id":"epithalong-10mg","title":"Epithalong 10mg","description":"\u003cp\u003e\u003cstrong\u003eBuy high-purity Epithalon in Australia (10mg). Third-party lab tested at \u0026gt;99% purity. Australian-domestic shipping, AUD pricing, supplied for laboratory research use only.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eAbout Epithalon\u003c\/h2\u003e\n\u003cp\u003eEpithalon (also spelled epitalon, and sometimes referenced as \"Epithalong\") is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly. It was derived from epithalamin, a polypeptide preparation of the pineal gland investigated extensively in the late twentieth century in Russian gerontology research. Epithalon distils that activity into a four-residue peptide and has since become a widely cited research compound in laboratory studies of telomere biology, circadian regulation, and cellular ageing.\u003c\/p\u003e\n\u003cp\u003eOptic Labs supplies Epithalon as a lyophilised research-grade peptide for laboratories investigating telomerase activity, pineal-axis signalling, and gene-expression changes associated with senescence. Each vial is third-party HPLC verified at \u0026gt;99% purity. Epithalon peptide is supplied for laboratory research use only and is not intended for human consumption, cosmetic application, or any therapeutic purpose.\u003c\/p\u003e\n\n\u003ch2\u003eProduct specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e Epithalon (Epitalon, Epithalong)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 307297-39-8\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C\u003csub\u003e14\u003c\/sub\u003eH\u003csub\u003e22\u003c\/sub\u003eN\u003csub\u003e4\u003c\/sub\u003eO\u003csub\u003e9\u003c\/sub\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e ~390.35 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Ala-Glu-Asp-Gly (AEDG)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% by HPLC\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvailable sizes:\u003c\/strong\u003e 10mg vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e 2–8°C, protect from light. Reconstituted: 2–8°C, used within 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Manufactured to research-grade specifications, third-party HPLC verified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShipping:\u003c\/strong\u003e Australia-wide domestic dispatch from Sydney, NSW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch background\u003c\/h2\u003e\n\u003cp\u003eEpithalon was developed by Vladimir Khavinson and colleagues at the St Petersburg Institute of Bioregulation and Gerontology as a short synthetic analogue of the pineal extract epithalamin. Across several decades of laboratory and clinical-population research, it has been investigated for effects on the pineal–melatonin axis, telomere maintenance, and biomarkers of biological ageing. Modern published research continues to use Epithalon as a probe for short-peptide regulation of gene expression.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTelomerase activity\u003c\/strong\u003e — in cell-culture studies, Epithalon has been reported to upregulate telomerase reverse transcriptase (hTERT) expression and extend telomere length in somatic cell lines.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePineal–melatonin axis\u003c\/strong\u003e — animal-model research has examined Epithalon's effect on pineal function, melatonin rhythm, and circadian regulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene-expression modulation\u003c\/strong\u003e — laboratory work has explored AEDG's interaction with histones and gene-promoter regions, characterising it as an epigenetic short-peptide regulator.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLifespan studies in animal models\u003c\/strong\u003e — published rodent studies have explored Epithalon's effect on median and maximum lifespan, age-related mortality, and tumour incidence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant and oxidative-stress markers\u003c\/strong\u003e — research has tracked changes in lipid peroxidation, glutathione, and other oxidative-stress markers in Epithalon-exposed tissue models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetinal and visual-system models\u003c\/strong\u003e — preclinical investigation has examined Epithalon in models of retinal degeneration and age-related ocular change.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunological ageing\u003c\/strong\u003e — laboratory studies have profiled changes in T-cell subsets and immune-marker expression in ageing animal models exposed to Epithalon.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor a more detailed research summary, see our \u003ca href=\"\/blogs\/news\/epithalon-australia-telomere-anti-aging-guide\"\u003eEpithalon telomere and anti-ageing research guide\u003c\/a\u003e and our \u003ca href=\"\/blogs\/news\/nad-plus-australia-longevity-research-guide\"\u003eNAD+ longevity research guide\u003c\/a\u003e. Researchers working with reconstitution should also reference our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003epeptide reconstitution guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eReconstitution and handling\u003c\/h2\u003e\n\u003cp\u003eEpithalon is supplied as a lyophilised powder and is reconstituted prior to use with sterile \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e. A common laboratory approach is to add 2 mL of bac water to a 10mg vial, yielding a 5 mg\/mL working concentration; at this concentration, 0.1 mL drawn into an insulin syringe corresponds to 500 µg of peptide. Reconstituted Epithalon should be stored at 2–8°C, protected from light, and used within 30 days. For step-by-step dilution mathematics, see our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e and our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage research guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eCommonly stacked research peptides\u003c\/h2\u003e\n\u003cp\u003eIn published longevity and ageing research, Epithalon is frequently grouped with other peptides and compounds investigated for cellular-ageing, mitochondrial and antioxidant research:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/nad-1000mg\"\u003eNAD+\u003c\/a\u003e — coenzyme central to sirtuin and DNA-repair pathways often co-studied with Epithalon in ageing research designs.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/mots-c-10mg-40mg\"\u003eMOTS-c\u003c\/a\u003e — mitochondrial-derived peptide cross-referenced with Epithalon in mitochondrial ageing research.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/glutathione-1500mg\"\u003eGlutathione\u003c\/a\u003e — endogenous tripeptide antioxidant studied alongside Epithalon in oxidative-stress and senescence models.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/ghk-cu-50mg-100mg\"\u003eGHK-Cu\u003c\/a\u003e — copper-binding tripeptide investigated for gene-expression and dermal-ageing research, often co-cited with Epithalon.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/cjc-1295-no-dac-ipamorelin-10mg\"\u003eCJC-1295 + Ipamorelin\u003c\/a\u003e — GH-axis blend cross-referenced in age-related endocrine research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor more on multi-peptide research designs, see our \u003ca href=\"\/blogs\/news\/peptide-research-stacks-australia-combinations\"\u003epeptide research stacks overview\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\n\u003ch3\u003eIs Epithalon legal in Australia?\u003c\/h3\u003e\n\u003cp\u003eEpithalon is supplied by Optic Labs strictly for laboratory research, development and analytical use. It is not approved by the Therapeutic Goods Administration for human therapeutic use and is not a registered medicine. For a detailed overview of Australian peptide research regulation, see our \u003ca href=\"\/blogs\/news\/are-peptides-legal-australia-tga-compliance-2025\"\u003eguide to peptide legality and TGA compliance in Australia\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhat is Epithalon?\u003c\/h3\u003e\n\u003cp\u003eEpithalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (AEDG), originally derived from the pineal-gland polypeptide complex epithalamin. It is investigated in laboratory research as a regulator of telomerase activity and gene expression. See our \u003ca href=\"\/blogs\/news\/epithalon-australia-telomere-anti-aging-guide\"\u003eEpithalon telomere research guide\u003c\/a\u003e for a deeper overview.\u003c\/p\u003e\n\n\u003ch3\u003eIs Epithalon the same as Epitalon or Epithalong?\u003c\/h3\u003e\n\u003cp\u003eYes — \"Epithalon\", \"Epitalon\" and \"Epithalong\" are spelling variants of the same AEDG tetrapeptide. They refer to the same compound across English, Russian transliteration, and various supplier brand names.\u003c\/p\u003e\n\n\u003ch3\u003eHow is Epithalon supplied?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs supplies Epithalon as a lyophilised powder in glass research vials, available in 10mg. Each vial is sealed and shipped with a tamper-evident seal. Certificates of analysis showing HPLC purity testing are available on request.\u003c\/p\u003e\n\n\u003ch3\u003eHow much bacteriostatic water do I mix with an Epithalon 10mg vial?\u003c\/h3\u003e\n\u003cp\u003eA common laboratory dilution is 2 mL of \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e per 10mg vial, giving a 5 mg\/mL solution. The exact volume depends on your research protocol — see our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e for dilution mathematics.\u003c\/p\u003e\n\n\u003ch3\u003eHow should reconstituted Epithalon be stored?\u003c\/h3\u003e\n\u003cp\u003eReconstituted Epithalon should be kept at 2–8°C, protected from light, and used within 30 days. Long-term storage of unreconstituted lyophilised powder should be at −20°C or colder. See our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage complete research guide\u003c\/a\u003e for handling detail.\u003c\/p\u003e\n\n\u003ch3\u003eWhere does Optic Labs ship to?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs ships Australia-wide from Sydney, NSW. Standard dispatch is next business day on orders received before the daily cut-off. International shipping is not currently offered.\u003c\/p\u003e\n\n\u003ch2\u003eLegal disclaimer\u003c\/h2\u003e\n\u003cp\u003eAll products on this site are supplied for \u003cstrong\u003elaboratory research, development or analytical use only\u003c\/strong\u003e. They are not for human consumption, clinical use, or any diagnostic, cosmetic or veterinary application. These products and statements have not been evaluated by the \u003cstrong\u003eTherapeutic Goods Administration (TGA)\u003c\/strong\u003e or the \u003cstrong\u003eAPVMA\u003c\/strong\u003e and are not intended to diagnose, treat, cure or prevent any disease. Optic Labs is not a \u003cstrong\u003ecompounding pharmacy\u003c\/strong\u003e or manufacturing facility as defined under the \u003cem\u003eTherapeutic Goods Act 1989\u003c\/em\u003e, and is not a registered provider of scheduled medicines or therapeutic goods.\u003c\/p\u003e","brand":"Optic Labs","offers":[{"title":"Default Title","offer_id":53360884777144,"sku":null,"price":52.99,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0952\/4196\/1656\/files\/epithalong_7735ba74-f28e-4539-9db9-4777cdbe7243.png?v=1776426194","url":"https:\/\/opticlabsau.com\/products\/epithalong-10mg","provider":"Optic Labs","version":"1.0","type":"link"}