{"product_id":"melanotan-2-10mg","title":"Melanotan 2 10mg","description":"\u003cp\u003e\u003cstrong\u003eBuy high-purity Melanotan-2 (10mg) in Australia. Third-party lab tested at \u0026gt;99% purity. Australian-domestic shipping, AUD pricing, supplied for laboratory research use only.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eAbout Melanotan-2\u003c\/h2\u003e\n\u003cp\u003eMelanotan-2 (MT-2) is a synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH), originally developed at the University of Arizona in the late 1980s as a research tool for studying the melanocortin receptor system.\u003c\/p\u003e\n\n\u003cp\u003eThe cyclic lactam bridge between Asp and Lys, together with the substitutions of Nle for Met and D-Phe for Phe, gives MT-2 substantially greater receptor-binding affinity, metabolic stability and functional duration than native α-MSH.\u003c\/p\u003e\n\n\u003cp\u003eIn published research, MT-2 is studied as a non-selective agonist of the melanocortin receptor family — primarily MC1R, MC3R and MC4R — and is one of the most extensively characterised research-grade melanocortin probes in the published literature.\u003c\/p\u003e\n\u003cp\u003eOptic Labs supplies Melanotan-2 as a lyophilised powder in 10mg research vials, third-party HPLC tested to \u0026gt;99% purity. The product is distributed Australian-domestic from Sydney, NSW, for in vitro and laboratory research applications. Melanotan-2 is supplied strictly for laboratory research, development or analytical use and is not intended for human consumption, cosmetic use or any therapeutic application.\u003c\/p\u003e\n\n\u003ch2\u003eProduct specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e Melanotan-2 (MT-2)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 121062-08-6\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C\u003csub\u003e50\u003c\/sub\u003eH\u003csub\u003e69\u003c\/sub\u003eN\u003csub\u003e15\u003c\/sub\u003eO\u003csub\u003e9\u003c\/sub\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e ~1024.18 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH\u003csub\u003e2\u003c\/sub\u003e (cyclic heptapeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% by HPLC\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvailable size:\u003c\/strong\u003e 10mg vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e 2–8°C, protect from light. Reconstituted: 2–8°C, used within 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Manufactured to research-grade specifications, third-party HPLC verified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShipping:\u003c\/strong\u003e Australia-wide domestic dispatch from Sydney, NSW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch background\u003c\/h2\u003e\n\u003cp\u003eMelanotan-2 was developed by Victor Hruby and colleagues at the University of Arizona as a stabilised, broad-spectrum analogue of α-MSH for use in melanocortin receptor research. The lactam-cyclised structure both restricts the peptide to its bioactive turn conformation and protects it from peptidase degradation, giving MT-2 a much longer functional half-life than the linear native hormone.\u003c\/p\u003e\n\n\u003cp\u003eThe same research programme later generated more selective analogues, including the MC4R-preferring compound bremelanotide (PT-141). MT-2 itself remains a standard pan-melanocortin agonist in research settings.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMelanocortin receptor pharmacology:\u003c\/strong\u003e in receptor-binding and cAMP accumulation assays, MT-2 acts as a non-selective agonist of MC1R, MC3R, MC4R and MC5R, with research interest in characterising downstream signalling profiles at each subtype.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMelanogenesis research:\u003c\/strong\u003e in melanocyte and melanoma cell-culture studies, MT-2 has been investigated for its effects on tyrosinase activity, MITF expression and the eumelanin\/pheomelanin synthesis ratio through MC1R activation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypothalamic energy balance:\u003c\/strong\u003e in rodent hypothalamic research, MT-2 has been examined as a tool for probing MC4R-mediated effects on food intake, body weight and adiposity in animal models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSexual function research:\u003c\/strong\u003e in published preclinical and clinical research, melanocortin receptor activation by MT-2 and the related selective analogue bremelanotide has been investigated in the context of central pathways involved in sexual behaviour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular and autonomic effects:\u003c\/strong\u003e in animal-model research, melanocortin receptor activation has been studied for effects on blood pressure, heart rate and central autonomic outflow.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammation and immune research:\u003c\/strong\u003e in cell-culture studies, melanocortin agonists have been examined for anti-inflammatory effects mediated through MC1R and MC3R on macrophages and other immune cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhotoprotection research:\u003c\/strong\u003e in cell and animal models, MC1R activation has been studied for its effects on UV-induced DNA damage repair and oxidative stress responses in melanocytes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor a plain-language overview of peptides, see our \u003ca href=\"\/blogs\/news\/what-are-peptides-australia-explainer\"\u003ewhat are peptides explainer\u003c\/a\u003e. Researchers working with reconstitution should also reference our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003epeptide reconstitution guide\u003c\/a\u003e, and for laboratory injection protocols our \u003ca href=\"\/blogs\/news\/how-to-inject-peptides-subcutaneous-protocol\"\u003esubcutaneous injection protocol article\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eReconstitution and handling\u003c\/h2\u003e\n\u003cp\u003eMelanotan-2 is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water before use in any laboratory protocol. A common laboratory approach for the 10mg vial is reconstitution in 2ml of \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e to yield a 5mg\/ml working stock, or in 1ml for a 10mg\/ml stock.\u003c\/p\u003e\n\n\u003cp\u003eThe bacteriostatic water should be drawn into a sterile syringe and injected slowly down the inside wall of the lyophilised vial, allowing the peptide cake to dissolve passively rather than through agitation. Reconstituted MT-2 should be aliquoted, refrigerated at 2–8°C and protected from light, with research stocks typically used within 30 days.\u003c\/p\u003e\n\n\u003cp\u003eFor dilution maths across alternative volumes, see our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e. For long-term storage protocols, see our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eCommonly stacked research peptides\u003c\/h2\u003e\n\u003cp\u003eIn published research and laboratory protocols, Melanotan-2 is examined alongside other melanocortin and pigmentation-pathway research compounds:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/pt-141-10mg\"\u003ePT-141 (bremelanotide)\u003c\/a\u003e — MC4R-preferring selective melanocortin agonist derived from the same research programme as MT-2.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/ghk-cu-50mg-100mg\"\u003eGHK-Cu\u003c\/a\u003e — copper tripeptide examined alongside MT-2 in skin, fibroblast and pigmentation-related research.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/glutathione-1500mg\"\u003eGlutathione\u003c\/a\u003e — co-investigated in melanocyte research for its role in tyrosinase activity and pheomelanin\/eumelanin balance.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/aod-9604-5mg\"\u003eAOD-9604\u003c\/a\u003e — examined alongside MT-2 in metabolic and adiposity research where melanocortin pathway involvement is relevant.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/reta-10mg-15mg-20mg-30mg\"\u003eRetatrutide\u003c\/a\u003e — metabolic research peptide co-investigated in studies of central energy balance pathways that intersect with the melanocortin system.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor broader context on combined research designs, see our \u003ca href=\"\/blogs\/news\/peptide-research-stacks-australia-combinations\"\u003epeptide research stacks overview\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\n\u003ch3\u003eIs Melanotan-2 legal in Australia?\u003c\/h3\u003e\n\u003cp\u003eMelanotan-2 is not registered with the Therapeutic Goods Administration (TGA) for any therapeutic or cosmetic use in Australia, and the TGA has previously issued public safety advisories regarding the importation of injectable melanocortin products. Optic Labs supplies Melanotan-2 strictly as a research chemical for in vitro and preclinical laboratory research — not for human consumption, cosmetic application or any therapeutic use.\u003c\/p\u003e\n\n\u003cp\u003eFor a full overview of how the TGA treats research peptides in Australia, see our \u003ca href=\"\/blogs\/news\/are-peptides-legal-australia-tga-compliance-2025\"\u003epeptide legality and TGA compliance guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhat is Melanotan-2?\u003c\/h3\u003e\n\u003cp\u003eMelanotan-2 is a synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH). In published research it acts as a non-selective agonist at the melanocortin receptor family (MC1R, MC3R, MC4R and MC5R) and is used as a research tool for probing melanocortin pharmacology. For a plain-language overview of peptides, see our \u003ca href=\"\/blogs\/news\/what-are-peptides-australia-explainer\"\u003ewhat are peptides explainer\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhat does Melanotan-2 do in published research?\u003c\/h3\u003e\n\u003cp\u003eIn published research, Melanotan-2 is studied for its effects on melanocortin receptor signalling, melanocyte tyrosinase activity and the eumelanin\/pheomelanin synthesis ratio (via MC1R), hypothalamic regulation of food intake and energy balance (via MC4R), central pathways relevant to sexual behaviour, and macrophage anti-inflammatory signalling (via MC1R\/MC3R). These observations are research findings only and do not constitute therapeutic, cosmetic or pigmentation-related claims.\u003c\/p\u003e\n\n\u003ch3\u003eHow does Melanotan-2 compare with PT-141 in research?\u003c\/h3\u003e\n\u003cp\u003eMelanotan-2 and \u003ca href=\"\/products\/pt-141-10mg\"\u003ePT-141 (bremelanotide)\u003c\/a\u003e were developed in the same research programme. MT-2 is a non-selective melanocortin agonist active at MC1R through MC5R, while PT-141 was engineered as a more MC4R-preferring analogue, removing some of the MC1R-mediated pigmentation activity. In research settings the two are used to probe distinct subsets of the melanocortin system.\u003c\/p\u003e\n\n\u003ch3\u003eHow is Melanotan-2 supplied?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs supplies Melanotan-2 as a lyophilised powder in 10mg glass research vials. Each vial is sealed with a tamper-evident closure. Certificates of analysis showing HPLC purity testing are available on request.\u003c\/p\u003e\n\n\u003ch3\u003eHow much bacteriostatic water do I mix with a 10mg Melanotan-2 vial?\u003c\/h3\u003e\n\u003cp\u003eFor a 10mg vial, 2ml of \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e yields a 5mg\/ml working stock; 1ml yields a 10mg\/ml stock; 5ml yields a 2mg\/ml stock. Choose a volume based on the concentrations required by the research protocol. For a worked example with unit conversions, see our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eHow should reconstituted Melanotan-2 be stored?\u003c\/h3\u003e\n\u003cp\u003eReconstituted Melanotan-2 should be stored at 2–8°C, protected from light, and used within approximately 30 days. For longer-term storage, aliquoting and freezing at −20°C or below is preferred to limit freeze-thaw degradation. Full handling protocols are covered in our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage research guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhere does Optic Labs ship to?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs ships Australia-wide from Sydney, NSW. Standard dispatch is next business day on orders received before the daily cut-off. International shipping is not currently offered.\u003c\/p\u003e\n\n\u003ch2\u003eLegal disclaimer\u003c\/h2\u003e\n\u003cp\u003eAll products on this site are supplied for \u003cstrong\u003elaboratory research, development or analytical use only\u003c\/strong\u003e. They are not for human consumption, clinical use, or any diagnostic, cosmetic or veterinary application. These products and statements have not been evaluated by the \u003cstrong\u003eTherapeutic Goods Administration (TGA)\u003c\/strong\u003e or the \u003cstrong\u003eAPVMA\u003c\/strong\u003e and are not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\n\u003cp\u003eOptic Labs is not a \u003cstrong\u003ecompounding pharmacy\u003c\/strong\u003e or manufacturing facility as defined under the \u003cem\u003eTherapeutic Goods Act 1989\u003c\/em\u003e, and is not a registered provider of scheduled medicines or therapeutic goods.\u003c\/p\u003e","brand":"Optic Labs","offers":[{"title":"Default Title","offer_id":53360884416696,"sku":null,"price":61.99,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0952\/4196\/1656\/files\/mt2-10.png?v=1776426194","url":"https:\/\/opticlabsau.com\/products\/melanotan-2-10mg","provider":"Optic Labs","version":"1.0","type":"link"}