{"product_id":"ss-31-10mg","title":"SS-31 10mg","description":"\u003cp\u003e\u003cstrong\u003eBuy high-purity SS-31 in Australia (10mg). Third-party lab tested at \u0026gt;99% purity. Australian-domestic shipping, AUD pricing, supplied for laboratory research use only.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eAbout SS-31\u003c\/h2\u003e\n\u003cp\u003eSS-31 (also known as elamipretide, MTP-131 or Bendavia) is a small mitochondria-targeted tetrapeptide developed in the laboratory of Hazel Szeto and Peter Schiller. The sequence — D-Arg-2',6'-dimethylTyr-Lys-Phe-NH\u003csub\u003e2\u003c\/sub\u003e — is engineered to selectively concentrate in the inner mitochondrial membrane, where it associates with cardiolipin and has been characterised for its effects on electron-transport efficiency, reactive oxygen species and ATP production in published research.\u003c\/p\u003e\n\n\u003cp\u003eSS-31 has become one of the most widely cited tools in mitochondrial-protection research over the past decade.\u003c\/p\u003e\n\u003cp\u003eOptic Labs supplies SS-31 in Australia as a lyophilised powder, 10mg per vial, third-party HPLC verified at \u0026gt;99% purity. The compound is provided strictly for laboratory research, including in-vitro mitochondrial function assays, cell-culture oxidative-stress models and animal studies of cardiac, renal, neurological and ageing biology. SS-31 is supplied for research use only and is not intended for human consumption, clinical, cosmetic, diagnostic or veterinary application.\u003c\/p\u003e\n\n\u003ch2\u003eProduct specifications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompound:\u003c\/strong\u003e SS-31 (elamipretide, MTP-131)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 736992-21-5\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C\u003csub\u003e32\u003c\/sub\u003eH\u003csub\u003e49\u003c\/sub\u003eN\u003csub\u003e9\u003c\/sub\u003eO\u003csub\u003e5\u003c\/sub\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e ~639.8 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e D-Arg-Dmt-Lys-Phe-NH\u003csub\u003e2\u003c\/sub\u003e (D-Arg-2',6'-dimethylTyr-Lys-Phe amide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% by HPLC\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvailable sizes:\u003c\/strong\u003e 10mg vial\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e 2–8°C, protect from light. Reconstituted: 2–8°C, used within 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Manufactured to research-grade specifications, third-party HPLC verified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShipping:\u003c\/strong\u003e Australia-wide domestic dispatch from Sydney, NSW\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eResearch background\u003c\/h2\u003e\n\u003cp\u003eSS-31 was first described in the early 2000s as part of the Szeto-Schiller (SS) series of cell-permeable, mitochondria-targeted antioxidant peptides. Unlike triphenylphosphonium-conjugated antioxidants, SS-31 concentrates in the inner mitochondrial membrane independent of membrane potential, where it interacts with cardiolipin. This pharmacophore has driven a sustained body of preclinical and clinical research into mitochondrial dysfunction.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCardiolipin binding and stabilisation of inner-mitochondrial-membrane cristae architecture in isolated mitochondria and cell-culture models.\u003c\/li\u003e\n\u003cli\u003eReductions in mitochondrial reactive oxygen species (ROS) generation and improved electron-transport-chain coupling in ischaemia-reperfusion models.\u003c\/li\u003e\n\u003cli\u003eCardioprotection in rodent models of myocardial infarction, heart failure and doxorubicin-induced cardiotoxicity.\u003c\/li\u003e\n\u003cli\u003eRenal-protection studies in models of acute kidney injury, ischaemia-reperfusion and chronic kidney disease.\u003c\/li\u003e\n\u003cli\u003eNeuroprotective signals in animal models of Parkinson's disease, traumatic brain injury and age-related cognitive decline.\u003c\/li\u003e\n\u003cli\u003eSkeletal-muscle research in ageing and disuse-atrophy models examining mitochondrial bioenergetics and fatigue resistance.\u003c\/li\u003e\n\u003cli\u003eInvestigation in primary mitochondrial diseases including Barth syndrome and mitochondrial myopathies through clinical research programmes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor broader mitochondrial-research context, see our \u003ca href=\"\/blogs\/news\/ss-31-mitochondrial-protection-research-guide\"\u003eSS-31 mitochondrial protection research guide\u003c\/a\u003e and our \u003ca href=\"\/blogs\/news\/mots-c-mitochondrial-peptide-longevity-research\"\u003eMOTS-c mitochondrial peptide guide\u003c\/a\u003e. Researchers working with reconstitution should also reference our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003epeptide reconstitution guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eReconstitution and handling\u003c\/h2\u003e\n\u003cp\u003eSS-31 is supplied lyophilised and should be reconstituted with sterile \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e for laboratory use. A common working approach is to add 2mL of bacteriostatic water to a 10mg vial, yielding a 5mg\/mL stock; 1mL gives 10mg\/mL for more concentrated workflows.\u003c\/p\u003e\n\n\u003cp\u003eAdd the diluent slowly down the side of the vial — do not inject directly onto the lyophilised cake — and allow the powder to dissolve without vigorous shaking. Reconstituted SS-31 should be stored at 2–8°C, protected from light, and used within 30 days.\u003c\/p\u003e\n\n\u003cp\u003eFor a step-by-step volume calculator and worked examples for any vial size, see our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003epeptide reconstitution calculator guide\u003c\/a\u003e and our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eCommonly stacked research peptides\u003c\/h2\u003e\n\u003cp\u003eSS-31 is frequently studied alongside other peptides relevant to mitochondrial function, longevity and tissue-repair pathways:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/mots-c-10mg-40mg\"\u003eMOTS-c\u003c\/a\u003e — mitochondrial-derived peptide examined in metabolic and exercise-mimetic research, complementary to SS-31 in mitochondrial-bioenergetics studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/nad-1000mg\"\u003eNAD+\u003c\/a\u003e — coenzyme central to electron transport and sirtuin signalling; commonly paired in mitochondrial-longevity research designs.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/epithalong-10mg\"\u003eEpithalon\u003c\/a\u003e — AEDG tetrapeptide investigated in telomerase and ageing-biology models.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/glutathione-1500mg\"\u003eGlutathione\u003c\/a\u003e — endogenous antioxidant tripeptide, often used as a reference compound in oxidative-stress assays.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/products\/ghk-cu-50mg-100mg\"\u003eGHK-Cu\u003c\/a\u003e — copper-binding tripeptide studied in mitochondrial-gene-expression and tissue-regeneration research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor broader stack-design context, see our \u003ca href=\"\/blogs\/news\/peptide-research-stacks-australia-combinations\"\u003epeptide research stacks overview\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\n\u003ch3\u003eIs SS-31 legal in Australia?\u003c\/h3\u003e\n\u003cp\u003eSS-31 is not an approved therapeutic good in Australia and is not registered with the Therapeutic Goods Administration (TGA). Optic Labs supplies SS-31 strictly for laboratory research, development and analytical use — not for human consumption, clinical or cosmetic application. For a detailed overview of how research peptides sit within the Australian regulatory framework, see our \u003ca href=\"\/blogs\/news\/are-peptides-legal-australia-tga-compliance-2025\"\u003eguide to peptide legality and TGA compliance in Australia\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhat is SS-31?\u003c\/h3\u003e\n\u003cp\u003eSS-31 is a synthetic mitochondria-targeted tetrapeptide (D-Arg-Dmt-Lys-Phe-NH\u003csub\u003e2\u003c\/sub\u003e), also known as elamipretide or MTP-131. It is one of the Szeto-Schiller series of peptides developed to concentrate in the inner mitochondrial membrane and interact with cardiolipin. For a plain-language overview of peptide structure and research use, see our \u003ca href=\"\/blogs\/news\/what-are-peptides-australia-explainer\"\u003ewhat are peptides explainer\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eHow does SS-31 differ from MOTS-c in mitochondrial research?\u003c\/h3\u003e\n\u003cp\u003eBoth compounds are studied in mitochondrial-function research but operate differently. SS-31 is a synthetic, mitochondria-targeted tetrapeptide that concentrates at cardiolipin in the inner mitochondrial membrane and is investigated for effects on cristae architecture, ROS and electron transport.\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA, studied as a metabolic regulator that signals to the nucleus. Researchers often examine the two in parallel rather than as substitutes — see our \u003ca href=\"\/blogs\/news\/mots-c-mitochondrial-peptide-longevity-research\"\u003eMOTS-c research guide\u003c\/a\u003e for context.\u003c\/p\u003e\n\n\u003ch3\u003eHow much bacteriostatic water do I mix with an SS-31 10mg vial?\u003c\/h3\u003e\n\u003cp\u003eFor a 10mg vial, 2mL of \u003ca href=\"\/products\/bac-water-3ml-10ml\"\u003ebacteriostatic water\u003c\/a\u003e gives a 5mg\/mL stock; 1mL gives 10mg\/mL. Choose the dilution that matches the volumes typical of your research protocol. See our \u003ca href=\"\/blogs\/news\/peptide-reconstitution-calculator-guide-australia\"\u003ereconstitution calculator guide\u003c\/a\u003e for worked examples.\u003c\/p\u003e\n\n\u003ch3\u003eHow should reconstituted SS-31 be stored?\u003c\/h3\u003e\n\u003cp\u003eReconstituted SS-31 should be stored at 2–8°C, protected from light, and used within 30 days. Lyophilised vials are stable at 2–8°C until reconstitution. For full handling guidance, see our \u003ca href=\"\/blogs\/news\/peptide-storage-complete-research-guide\"\u003epeptide storage research guide\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eWhere does Optic Labs ship to?\u003c\/h3\u003e\n\u003cp\u003eOptic Labs ships Australia-wide from Sydney, NSW. Standard dispatch is next business day on orders received before the daily cut-off. International shipping is not currently offered.\u003c\/p\u003e\n\n\u003ch2\u003eLegal disclaimer\u003c\/h2\u003e\n\u003cp\u003eAll products on this site are supplied for \u003cstrong\u003elaboratory research, development or analytical use only\u003c\/strong\u003e. They are not for human consumption, clinical use, or any diagnostic, cosmetic or veterinary application. These products and statements have not been evaluated by the \u003cstrong\u003eTherapeutic Goods Administration (TGA)\u003c\/strong\u003e or the \u003cstrong\u003eAPVMA\u003c\/strong\u003e and are not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\n\u003cp\u003eOptic Labs is not a \u003cstrong\u003ecompounding pharmacy\u003c\/strong\u003e or manufacturing facility as defined under the \u003cem\u003eTherapeutic Goods Act 1989\u003c\/em\u003e, and is not a registered provider of scheduled medicines or therapeutic goods.\u003c\/p\u003e","brand":"Optic Labs","offers":[{"title":"Default Title","offer_id":53360884121784,"sku":null,"price":61.99,"currency_code":"AUD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0952\/4196\/1656\/files\/ss31.png?v=1776426119","url":"https:\/\/opticlabsau.com\/products\/ss-31-10mg","provider":"Optic Labs","version":"1.0","type":"link"}