TB-500 5mg / 10mg

Buy high-purity TB-500 in Australia (5mg / 10mg). Third-party lab tested at >99% purity. Australian-domestic shipping, AUD pricing, supplied for laboratory research use only.

About TB-500

TB-500 is a synthetic 17-amino-acid peptide corresponding to the active region (residues 17-23) of Thymosin Beta-4 (Tβ4), a naturally occurring protein found in nearly all human and mammalian tissues. Optic Labs supplies TB-500 as a high-purity lyophilised powder in 5mg and 10mg vials, packaged for in vitro and preclinical laboratory research. Each batch is independently HPLC-tested for purity and identity, with certificates of analysis available on request.

TB-500 has been extensively studied in the regenerative biology, cell migration and angiogenesis literature. Published research has investigated its effects on actin sequestration, endothelial cell migration, fibroblast activity and tissue-repair processes in animal-model and cell-culture systems. Optic Labs supplies the compound for laboratory research only — not for human consumption, clinical use, or any therapeutic application.

Product specifications

• Compound: TB-500 (Thymosin Beta-4 fragment 17-23, acetylated)
• CAS number: 77591-33-4 (Tβ4 parent), TB-500 fragment
• Molecular formula: C₃₄H₅₆N₁₀O₁₃ (peptide fragment)
• Molecular weight: ~889.0 g/mol (TB-500 fragment)
• Sequence (Tβ4 17-23 region): Ac-LKKTETQ-OH
• Form: Lyophilised (freeze-dried) white powder
• Purity: >99% by HPLC
• Available sizes: 5mg vial / 10mg vial
• Storage: Store unreconstituted vials at 2–8°C; protect from light. Reconstituted solution stored at 2–8°C and used within 30 days.
• Origin: Manufactured to research-grade specifications, third-party HPLC verified
• Shipping: Australia-wide domestic dispatch from Sydney, NSW

Research background

Thymosin Beta-4 was first identified in the 1980s as a major actin-sequestering protein in eukaryotic cells. The TB-500 fragment used in research preserves the central actin-binding motif of the parent peptide. Published preclinical studies have examined TB-500 in the context of:

• Actin sequestration and cytoskeletal remodelling in cell-culture models
• Endothelial cell migration and capillary tube formation
• Cardiac, skin and corneal wound-healing animal models
• Fibroblast and myocyte proliferation studies
• Anti-inflammatory and matrix-metalloproteinase pathway research

For a more detailed research summary with study citations, see our TB-500 thymosin research guide and our BPC-157 + TB-500 stack research guide. Researchers working with reconstitution should also reference our peptide reconstitution guide.

Reconstitution and handling

TB-500 is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water before use in any laboratory protocol. A typical reconstitution for a 5mg vial is 2mL of bacteriostatic water, yielding a working concentration of 2.5mg/mL; for a 10mg vial, 2mL yields 5mg/mL. Exact volumes should be calculated for each protocol — our reconstitution calculator guide walks through the maths. Reconstituted vials should be stored refrigerated at 2–8°C and protected from light.

Commonly stacked research peptides

TB-500 is frequently studied alongside other regenerative peptides in published animal-model literature. Researchers working on combined regenerative protocols may be interested in:

• BPC-157 — most frequently co-investigated peptide for tissue-repair research
• BPC-157 + TB-500 blend — pre-mixed convenience option
• GHK-Cu — collagen and skin regeneration research
• GLOW Stack — BPC-157 + GHK-Cu + TB-500 combined
• KLOW Stack — adds KPV for inflammatory pathway research

Frequently asked questions

Is TB-500 legal in Australia?

TB-500 is not currently approved by the Therapeutic Goods Administration (TGA) for any therapeutic use in Australia. Optic Labs supplies TB-500 strictly as a research chemical for in vitro and preclinical laboratory research — not for human consumption, clinical use or any therapeutic application. For a detailed overview of how Australian peptide regulation works, see our guide to peptide legality and TGA compliance in Australia.

What is TB-500?

TB-500 is a synthetic 7-amino-acid peptide fragment corresponding to the central actin-binding region (residues 17-23) of Thymosin Beta-4, a naturally occurring intracellular protein. In published research it has been investigated for its effects on cell migration, angiogenesis and tissue-repair signalling in animal and cell-culture models. See our TB-500 research guide for background.

What is the difference between TB-500 and Thymosin Beta-4?

Thymosin Beta-4 (Tβ4) is the full 43-amino-acid parent protein. TB-500 refers to a shorter synthetic fragment (residues 17-23) that retains the actin-binding motif. The shorter sequence is the form most commonly used in commercially supplied research peptide work. Our research guide covers the differences in detail.

How is TB-500 supplied?

Optic Labs supplies TB-500 as a lyophilised (freeze-dried) white powder in glass research vials, available in 5mg and 10mg sizes. Each vial is sealed and shipped with a tamper-evident seal. Certificates of analysis showing HPLC purity testing are available on request.

How much bacteriostatic water do I mix with a 5mg or 10mg TB-500 vial?

Reconstitution volume depends on the working concentration required by the research protocol. As a common starting point, 2mL of bacteriostatic water reconstitutes a 5mg vial at 2.5mg/mL, or a 10mg vial at 5mg/mL. Our reconstitution guide covers the calculations in detail.

How should reconstituted TB-500 be stored?

Unreconstituted vials should be stored at 2–8°C and protected from light. Once reconstituted, the solution should be refrigerated at 2–8°C and used within approximately 30 days. For full storage protocols across all peptide forms, see our peptide storage guide.

Where does Optic Labs ship to?

Optic Labs ships Australia-wide from Sydney, NSW. Standard dispatch is next business day on orders received before the daily cut-off. International shipping is not currently offered.

Legal disclaimer

All products on this site are supplied for laboratory research, development or analytical use only. They are not for human consumption, clinical use, or any diagnostic, cosmetic or veterinary application. These products and statements have not been evaluated by the Therapeutic Goods Administration (TGA) or the APVMA and are not intended to diagnose, treat, cure or prevent any disease. Optic Labs is not a compounding pharmacy or manufacturing facility as defined under the Therapeutic Goods Act 1989, and is not a registered provider of scheduled medicines or therapeutic goods.